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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
1987-2-5
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pubmed:abstractText |
This preliminary study examined the healing following an experimental procedure designed to facilitate coronal migration of progenitor cells from the periodontal ligament circumferentially on roots of premolar teeth in beagle dogs. Mucoperiosteal flaps were reflected on the buccal and lingual aspects of premolars in six beagle dogs with periodontal disease. Following root preparation, pieces of orthodontic wire were placed interproximally on the crowns to bridge the spaces between teeth. Biobrane, a synthetic membrane bonded to a knitted nylon fabric and coated with collagen, was placed as a physical barrier between the roots and the flaps to be replaced. The membrane extended as a single piece from the cementoenamel junction (CEJ) to overlap the crest of alveolar bone by 3 to 4 mm on both the buccal and lingual surfaces of the three premolars in each quadrant. The membrane was attached to the crowns at the CEJ with resin. The flaps were replaced and sutured. Postoperative care included plaque control and the membranes were removed after 5 weeks. The dogs were sacrificed to provide observation periods of 8 and 16 weeks after placement of membranes. Histologic examination revealed new connective tissue attachment in the apical part of the 8- and 16-week experimental specimens. Some experimental specimens showed new attachment up to 2.94 mm while others showed a long junctional epithelium (JE). Root resorption was also seen in some specimens. These preliminary findings suggest that placement of physical barriers between root surface and flaps may be beneficial in facilitating coronal migration of progenitor cells from the periodontal ligament.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
D
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
|
pubmed:issn |
0022-3492
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
57
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
727-34
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:3467057-Animals,
pubmed-meshheading:3467057-Connective Tissue,
pubmed-meshheading:3467057-Dental Cementum,
pubmed-meshheading:3467057-Dental Enamel,
pubmed-meshheading:3467057-Dogs,
pubmed-meshheading:3467057-Epithelium,
pubmed-meshheading:3467057-Gingiva,
pubmed-meshheading:3467057-Membranes, Artificial,
pubmed-meshheading:3467057-Periodontal Ligament,
pubmed-meshheading:3467057-Periodontitis,
pubmed-meshheading:3467057-Regeneration,
pubmed-meshheading:3467057-Surgical Flaps,
pubmed-meshheading:3467057-Tooth Root
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pubmed:year |
1986
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pubmed:articleTitle |
Guided tissue regeneration. An experimental procedure in beagle dogs.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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