Linked Life Data

3463169

Source:http://linkedlifedata.com/resource/pubmed/id/3463169

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3-4
pubmed:dateCreated
1986-9-26
pubmed:abstractText
The effect of Al(OH)3 was investigated on the gastric bleeding induced by acetylsalicylic acid + HCl. Cats provided with Heidenhain pouches were used. The pouch had vascular connections to the main stomach. Instillation of acidified acetylsalicylic acid into the pouch caused a marked increase in its blood content indicating the development of hemorrhagic mucosal damages. The blood loss was totally abolished by administration of Al(OH)3 into the main stomach. We, therefore, conclude that Al(OH)3 induced an enhanced release of PGE2 into the submucosa. PGE2 reached the pouch via connecting vessels originated from the main stomach. The results indicate that certain antacids induce the release of prostaglandins not only into the gastric lumen but also in the submucosa.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0065-4299
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
372-4
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Aluminium hydroxide inhibits acetylsalicylic acid-induced gastric erosions in cats with Heidenhain-pouch.
pubmed:publicationType
Journal Article