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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1986-7-24
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pubmed:abstractText |
A study of 347 patients with gastrointestinal diseases revealed elevation of CA125 in sera of 63% of patients with pancreatic carcinoma, 46% of patients with carcinoma of the biliary tract, 40% of patients with liver carcinoma and 11-37% of patients with other carcinomas. All of the patients with acute pancreatitis, chronic pancreatitis, cholelithiasis, and peptic ulcer had normal CA125 values, but 35% of patients with liver cirrhosis and 10% of patients with chronic active hepatitis had elevated values. Patients with disseminated carcinomas had significantly higher levels than patients with localized carcinomas. CA125 did not significantly correlate with CA19-9 or carcinoembryonic antigen in patients with pancreatic carcinoma. Ninety-seven percent of patients with pancreatic carcinoma were defined as being positive when both serum CA125 and CA19-9 were evaluated. These results indicate that CA125 is useful for differentiating pancreatic carcinoma from chronic pancreatitis, especially when supplemented with CA19-9.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0002-9629
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
292
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
30-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3459357-Antigens, Neoplasm,
pubmed-meshheading:3459357-Antigens, Surface,
pubmed-meshheading:3459357-Antigens, Tumor-Associated, Carbohydrate,
pubmed-meshheading:3459357-Carcinoembryonic Antigen,
pubmed-meshheading:3459357-Colonic Neoplasms,
pubmed-meshheading:3459357-Gastrointestinal Diseases,
pubmed-meshheading:3459357-Gastrointestinal Neoplasms,
pubmed-meshheading:3459357-Humans,
pubmed-meshheading:3459357-Liver Diseases,
pubmed-meshheading:3459357-Pancreatic Diseases,
pubmed-meshheading:3459357-Pancreatic Neoplasms,
pubmed-meshheading:3459357-Stomach Neoplasms
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pubmed:year |
1986
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pubmed:articleTitle |
Clinical significance of serum CA125 values in patients with cancers of the digestive system.
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pubmed:publicationType |
Journal Article,
Comparative Study
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