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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4748
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pubmed:dateCreated |
1986-4-29
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pubmed:abstractText |
The Hu-ets-1 oncogene was found to be rearranged and amplified 30-fold in one case of acute myelomonocytic leukemia in which a homogeneously staining region occurred on 11q23; the oncogene was rearranged and amplified approximately tenfold in a case of small lymphocytic cell lymphoma with an inverted insertion that also involved band 11q23. This work suggests that Hu-ets-1 is an unusual oncogene that can help explain the common involvement of chromosome band 11q23 in various subtypes of hematopoietic malignancies.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0036-8075
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
18
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pubmed:volume |
232
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
398-400
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:3457468-Chromosome Aberrations,
pubmed-meshheading:3457468-Chromosome Banding,
pubmed-meshheading:3457468-Chromosome Disorders,
pubmed-meshheading:3457468-Chromosome Mapping,
pubmed-meshheading:3457468-Chromosomes, Human, 13-15,
pubmed-meshheading:3457468-Chromosomes, Human, 6-12 and X,
pubmed-meshheading:3457468-DNA, Neoplasm,
pubmed-meshheading:3457468-Humans,
pubmed-meshheading:3457468-Leukemia, Myeloid, Acute,
pubmed-meshheading:3457468-Lymphoma, Non-Hodgkin,
pubmed-meshheading:3457468-Nucleic Acid Hybridization,
pubmed-meshheading:3457468-Oncogenes,
pubmed-meshheading:3457468-Translocation, Genetic
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pubmed:year |
1986
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pubmed:articleTitle |
Amplification and rearrangement of Hu-ets-1 in leukemia and lymphoma with involvement of 11q23.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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