Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
|
pubmed:dateCreated |
1986-3-10
|
pubmed:abstractText |
A patient with chronic myelogenous leukemia (CML) associated with a remarkable increase of micromegakaryocytes in bone marrow was revealed to have an abnormality of a long arm of chromosome #3, i.e., inv(3)(q21q26), in addition to a complex Ph translocation: t(9;22;15)(q34;q11;q22). Although several cases of acute leukemia with inv(3)(q21q26) and abnormal megakaryocytes have been reported, this is the first case in which the association of inv(3)(q21q26) with a megakaryocytic abnormality was observed in a patient with CML. Our findings suggest that this structural rearrangement may be more specifically associated with abnormal thrombopoiesis than are other structural anomalies of 3q.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0165-4608
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
20
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
121-7
|
pubmed:dateRevised |
2009-11-19
|
pubmed:meshHeading |
pubmed-meshheading:3455854-Blood Platelets,
pubmed-meshheading:3455854-Chromosome Inversion,
pubmed-meshheading:3455854-Chromosomes, Human, 1-3,
pubmed-meshheading:3455854-Hematopoiesis,
pubmed-meshheading:3455854-Humans,
pubmed-meshheading:3455854-Leukemia, Myeloid,
pubmed-meshheading:3455854-Male,
pubmed-meshheading:3455854-Megakaryocytes,
pubmed-meshheading:3455854-Middle Aged,
pubmed-meshheading:3455854-Philadelphia Chromosome,
pubmed-meshheading:3455854-Platelet Count
|
pubmed:year |
1986
|
pubmed:articleTitle |
Inversion of chromosome 3 in a case of chronic myelogenous leukemia with abnormal thrombopoiesis.
|
pubmed:publicationType |
Journal Article,
Case Reports
|