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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1988-9-15
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pubmed:abstractText |
We have studied the changes in the activity of the pentose phosphate cycle and the malic enzyme produced by the activation or inhibition of different NADPH-consuming pathways. Kynurenate, an acetyl-CoA-carboxylase inhibitor produced a decrease in the flux through the NADPH-producing pathways pentose phosphate cycle and malic enzyme. Acini (isolated from mammary gland) incubated in the presence of ter-butyl-hydroperoxide, a compound which is metabolized via a NADPH-consuming pathway, showed a substantial increase in the pentose phosphate cycle and the malic enzyme pathways.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0158-5231
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
957-62
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3454650-Animals,
pubmed-meshheading:3454650-Enzyme Activation,
pubmed-meshheading:3454650-Female,
pubmed-meshheading:3454650-Kynurenic Acid,
pubmed-meshheading:3454650-Malate Dehydrogenase,
pubmed-meshheading:3454650-Mammary Glands, Animal,
pubmed-meshheading:3454650-NADP,
pubmed-meshheading:3454650-Pentose Phosphate Pathway,
pubmed-meshheading:3454650-Peroxides,
pubmed-meshheading:3454650-Rats,
pubmed-meshheading:3454650-Rats, Inbred Strains,
pubmed-meshheading:3454650-tert-Butylhydroperoxide
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pubmed:year |
1987
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pubmed:articleTitle |
The NADPH-producing pathways (pentose phosphate and malic enzyme) are regulated by the NADPH consumption in rat mammary gland.
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pubmed:affiliation |
Departamento de Bioquímica, Facultad de Farmacia, Universidad de Sevilla, Spain.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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