Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1988-8-24
pubmed:abstractText
Glomeruli isolated from three male dogs affected with Samoyed hereditary glomerulopathy were compared by scanning electron microscopy with glomeruli of one carrier female and six unaffected dogs. Scanning electron microscopy was performed before and after removal of podocytes and endothelial cells with enzyme and detergent, producing cellular and acellular glomeruli respectively. Cellular glomeruli of unaffected dogs showed podocytes with normally arranged foot processes, while in acellular glomeruli, the subepithelial surface of glomerular capillary basement membranes appeared smooth to finely granular. In contrast, cellular glomeruli of affected males showed microvilli, globular cytoplasmic projections from podocytes, and effacement of foot processes; acellular glomeruli demonstrated ridges and plaque-like irregularities on the subepithelial surface of glomerular capillary basement membranes. Changes in the glomeruli of the carrier female were intermediate between those of unaffected and affected male dogs. The appearance of the subepithelial surface of glomerular capillary basement membranes of acellular glomeruli seen by scanning electron microscopy correlated with the extent of multilaminar splitting of glomerular capillary basement membranes seen by transmission electron microscopy.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/3453267-14829136, http://linkedlifedata.com/resource/pubmed/commentcorrection/3453267-2409091, http://linkedlifedata.com/resource/pubmed/commentcorrection/3453267-2870585, http://linkedlifedata.com/resource/pubmed/commentcorrection/3453267-3711721, http://linkedlifedata.com/resource/pubmed/commentcorrection/3453267-3799818, http://linkedlifedata.com/resource/pubmed/commentcorrection/3453267-3892134, http://linkedlifedata.com/resource/pubmed/commentcorrection/3453267-3941544, http://linkedlifedata.com/resource/pubmed/commentcorrection/3453267-3946299, http://linkedlifedata.com/resource/pubmed/commentcorrection/3453267-4014431, http://linkedlifedata.com/resource/pubmed/commentcorrection/3453267-4054891, http://linkedlifedata.com/resource/pubmed/commentcorrection/3453267-5074843, http://linkedlifedata.com/resource/pubmed/commentcorrection/3453267-5483882, http://linkedlifedata.com/resource/pubmed/commentcorrection/3453267-599902, http://linkedlifedata.com/resource/pubmed/commentcorrection/3453267-6085433, http://linkedlifedata.com/resource/pubmed/commentcorrection/3453267-6222217, http://linkedlifedata.com/resource/pubmed/commentcorrection/3453267-6274634, http://linkedlifedata.com/resource/pubmed/commentcorrection/3453267-6612089, http://linkedlifedata.com/resource/pubmed/commentcorrection/3453267-6742105, http://linkedlifedata.com/resource/pubmed/commentcorrection/3453267-6888960, http://linkedlifedata.com/resource/pubmed/commentcorrection/3453267-7062344, http://linkedlifedata.com/resource/pubmed/commentcorrection/3453267-7382748
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0830-9000
pubmed:author
pubmed:issnType
Print
pubmed:volume
51
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
475-80
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Scanning electron microscopy of cellular and acellular glomeruli of male dogs affected with Samoyed hereditary glomerulopathy and a carrier female.
pubmed:affiliation
Ontario Veterinary College, University of Guelph.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't