Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1988-6-16
pubmed:abstractText
A selective difference spectrophotometric assay for 5-hydroxymethylfurfuraldehyde (5-HMF) in injectable solutions of dextrose is described, which eliminates the interference that occurs in simple direct spectrophotometric procedures from other ultraviolet absorbing substances in the solution. The assay is based on the measurement of the absorbance of 5-HMF in an aliquot of the injection relative to that of an equimolar solution in which the 5-HMF has been reduced by sodium borohydride. The difference absorbance, which is due to the loss of absorption after reduction of 5-HMF, is proportional to the concentration of 5-HMF and is free from interference from the ingredients of the formulations and from other UV-absorbing decomposition products of dextrose.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0269-4727
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
11-8
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
The difference spectrophotometric assay of 5-hydroxymethylfurfuraldehyde in parenteral formulations of dextrose.
pubmed:affiliation
Department of Pharmacy, University of Strathclyde, Glasgow, U.K.
pubmed:publicationType
Journal Article