Linked Life Data

3444599

Source:http://linkedlifedata.com/resource/pubmed/id/3444599

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1988-5-11
pubmed:abstractText
This study was undertaken to identify features of optic nerve head architecture that might explain, in part, why ganglion cell loss occurs in patients with low-tension glaucoma. We compared retrospectively the disc photographs of 25 patients with low-tension glaucoma with those of 26 control patients with typical open-angle glaucoma. No differences were observed in any of the following features: pore length, shape, or size variation; cup/disc and disc/arteriole ratio; clock positions of total rim loss; central retinal vessel entry site; rim pallor; number of rim-crossing vessels; and presence or absence of peripapillary nerve fiber layer hemorrhages, optic pits, and central retinal vessel canals. An hour-glass appearance of connective tissue bundles within the scleral lamina cribrosa, however, was present statistically less often in patients with low-tension glaucoma (p = 0.007). We speculate that the microscopic arrangement of fiber bundles within the lamina cribrosa may play an etiologic role in the pathogenesis of low-tension glaucoma.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0022-023X
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
882-9
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Comparison of optic disc features in low-tension and typical open-angle glaucoma.
pubmed:affiliation
Wilmer Institute, Johns Hopkins Hospital, Baltimore, Maryland 21205.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't