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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1988-4-4
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pubmed:abstractText |
In goats, there was a linear correlation of area under the plasma concentration-time curve (AUC) with dose in the range 0-20 mg/kg as single dosages of oxfendazole (OFZ). The bioavailability of OFZ after oral administration was lower in goats than in sheep. The repetition of three administrations at 24 h intervals produced significant increase in the AUC in comparison with a single administration equivalent to the total dosage (1 X 5.0 and 3 X 1.7 mg/kg). Infection with O. circumcincta produced a 33% decrease in the bioavailability of OFZ.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0140-7783
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
10
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
305-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3437495-Administration, Oral,
pubmed-meshheading:3437495-Animals,
pubmed-meshheading:3437495-Anthelmintics,
pubmed-meshheading:3437495-Benzimidazoles,
pubmed-meshheading:3437495-Biological Availability,
pubmed-meshheading:3437495-Goats,
pubmed-meshheading:3437495-Injections, Intravenous,
pubmed-meshheading:3437495-Ostertagiasis,
pubmed-meshheading:3437495-Sheep
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pubmed:year |
1987
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pubmed:articleTitle |
Pharmacokinetics of oxfendazole in goats: a comparison with sheep.
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pubmed:affiliation |
Department of Veterinary Pharmacology, Veterinary School of Glasgow, U.K.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|