Linked Life Data

3437473

Source:http://linkedlifedata.com/resource/pubmed/id/3437473

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1988-4-1
pubmed:abstractText
This study examined the effects of dietary taurine deprivation on visual development in rhesus monkeys. From birth to 3 months of age, rhesus monkeys were fed a taurine-free, soy protein-based infant formula, or the same formula supplemented with taurine. The early postnatal development of visual function was assessed with behavioral measurements of visual acuity. Plasma taurine levels in the taurine-deprived group fell to 35-50% of control values, as in human infants fed similar formulas. The visual acuity of the taurine-deprived infants was significantly impaired: acuity thresholds differed from control values by nearly a factor of 2 at 4, 8, and 12 weeks of age. The loss of acuity is associated with morphological changes in photoreceptors, particularly cones in the foveal region. These results provide direct evidence that taurine is essential for normal visual development in primates, and they support the nutritional importance of taurine for human infants.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0360-4012
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
597-601
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Visual acuity loss in rhesus monkey infants fed a taurine-free human infant formula.
pubmed:affiliation
Division of Metabolic and Immune Diseases, Oregon Regional Primate Research Center, Beaverton 97006.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.