Linked Life Data

3436844

Source:http://linkedlifedata.com/resource/pubmed/id/3436844

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1988-3-25
pubmed:abstractText
While modern neuropsychological and electrophysiological studies claim a functional disturbance of the left hemisphere (LH) in schizophrenia, historical clinical and anatomical work rather points to the right hemisphere (RH) as the main site of psychosis. In the light of an interhemispheric functional balance of inhibition and release, LH-dysfunction in schizophrenia could be interpreted as a consequence of an overactive and inhibiting RH. Since the RH is especially activated by emotional stimuli, and exaggerated distractability and sensitivity to emotional stimuli are hallmarks of schizophrenia, we compared the emotional irritability of the RH and LH in 35 acute schizophrenics and 22 matched controls. Using tachistoscopic half-field presentation we found in acute schizophrenics a selective impairment of RH-function with simultaneous improvement of LH-performance induced by emotional distractors. We therefore suggest that a right hemispheric dysfunction and hypersensitivity to emotional material plays an essential catalytic role in acute schizophrenia.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0167-8760
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
261-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Schizophrenia--an emotional hypersensitivity of the right cerebral hemisphere.
pubmed:affiliation
Abteilung Allgemeine Psychiatrie, Albert-Ludwigs-Universität, Freiburg, F.R.G.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't