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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1978-4-17
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pubmed:abstractText |
The effects of 5 and 10 mg oral nitrazepam doses on manual skills, grip strength, and reaction time 8 hours after ingestion of the drugs were studied in 34 healthy female volunteers aged 19-22 years. 5 mg nitrazepam caused a slight but insignificant decrease in psychomotor skills. With 10 mg psychomotor skills were influenced significantly. Grip strength and reaction time were not influenced either by the 5 or 10 mg doses. The investigators corroborate the value of the established effects of nitrazepam as a hypnotic, but recommend that caution should be excercised in prescribing the drug as a hypnotic (especially in doses exceeding 5 mg) to work-aged subjects as there is a risk of significant effect on the psychomotor skills. Furthermore, the drug may cause fatigue.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0001-6683
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
42
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
130-4
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pubmed:dateRevised |
2009-10-27
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pubmed:meshHeading |
pubmed-meshheading:343500-Adult,
pubmed-meshheading:343500-Clinical Trials as Topic,
pubmed-meshheading:343500-Drug Evaluation,
pubmed-meshheading:343500-Female,
pubmed-meshheading:343500-Humans,
pubmed-meshheading:343500-Motor Activity,
pubmed-meshheading:343500-Motor Skills,
pubmed-meshheading:343500-Muscle Contraction,
pubmed-meshheading:343500-Nitrazepam,
pubmed-meshheading:343500-Reaction Time,
pubmed-meshheading:343500-Sleep
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pubmed:year |
1978
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pubmed:articleTitle |
The effect of nitrazepam on manual skill, grip strength, and reaction time with special reference to subjective evaluation of effects on sleep.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Controlled Clinical Trial
|