Linked Life Data

3430648

Source:http://linkedlifedata.com/resource/pubmed/id/3430648

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1988-3-7
pubmed:abstractText
Early effects of alloxan on structure and function of rat submandibular gland were investigated by light and electron microscopy, X-ray microanalysis, and by analysis of secreted saliva. Alloxan induced, already within 3 h, intracellular accumulation of mucus, as also evidenced by an increase in the cellular calcium concentration. In addition, 3 to 6 h after injection of alloxan, the granular duct cells were found to be vacuolated, which could suggest a cytotoxic effect of alloxan on this cell type. Alloxan did not significantly affect the flow rate of submandibular saliva after pilocarpine stimulation, and also did not significantly alter the concentrations of sodium, potassium, calcium and protein in the final saliva. The effects of alloxan on the acinar cells of the rat submandibular gland and the absence of effects on fluid secretion by this gland are in accordance with a direct or indirect inhibition of the cAMP system.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0022-4782
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
555-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Early effects of alloxan on rat submandibular gland.
pubmed:affiliation
Department of Ultrastructure Research, University of Stockholm, Sweden.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't