| pubmed-article:3429640 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3429640 | lifeskim:mentions | umls-concept:C1123023 | lld:lifeskim |
| pubmed-article:3429640 | lifeskim:mentions | umls-concept:C0220806 | lld:lifeskim |
| pubmed-article:3429640 | lifeskim:mentions | umls-concept:C0085979 | lld:lifeskim |
| pubmed-article:3429640 | lifeskim:mentions | umls-concept:C1267092 | lld:lifeskim |
| pubmed-article:3429640 | lifeskim:mentions | umls-concept:C0227365 | lld:lifeskim |
| pubmed-article:3429640 | lifeskim:mentions | umls-concept:C0424790 | lld:lifeskim |
| pubmed-article:3429640 | lifeskim:mentions | umls-concept:C0035028 | lld:lifeskim |
| pubmed-article:3429640 | lifeskim:mentions | umls-concept:C0030685 | lld:lifeskim |
| pubmed-article:3429640 | lifeskim:mentions | umls-concept:C0680255 | lld:lifeskim |
| pubmed-article:3429640 | lifeskim:mentions | umls-concept:C0391871 | lld:lifeskim |
| pubmed-article:3429640 | lifeskim:mentions | umls-concept:C1283071 | lld:lifeskim |
| pubmed-article:3429640 | lifeskim:mentions | umls-concept:C1963578 | lld:lifeskim |
| pubmed-article:3429640 | lifeskim:mentions | umls-concept:C0718263 | lld:lifeskim |
| pubmed-article:3429640 | lifeskim:mentions | umls-concept:C0146894 | lld:lifeskim |
| pubmed-article:3429640 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:3429640 | pubmed:dateCreated | 1988-3-15 | lld:pubmed |
| pubmed-article:3429640 | pubmed:abstractText | The mechanical events following release of ATP from P3-1-(2-nitro)phenylethyladenosine-5'-triphosphate (caged-ATP) in skinned guinea pig taenia coli smooth muscle in rigor were investigated. A rigor force of about 25-35% of the maximal active force was obtained by removing ATP at the plateau of a maximal active contraction. In the rigor solution free-Mg2+ was 2 mM, ionic strength 90 mM and pH 7.0. When caged-ATP (12.5 mM) was diffused into the preparation there was no change in the rigor force. Photolytic production of about 2 mM ATP was achieved with a xenon flash lamp. Following illumination, force decreased with an approximate initial rate constant of 0.7 s-1. The rate of relaxation was increased in the presence of inorganic phosphate (at 3 mM: 1.3 s-1; 10 mM: 2.2 s-1). At higher Mg2+ concentrations the rate of relaxation was slower (5 mM: 0.2 s-1) and at lower concentrations the rate was faster (0.5 mM: 1.2 s-1). An increased rate of relaxation was observed when ionic strength was increased to 150 mM (2.2 s-1). Phosphate increased the rate of relaxation at the different levels of Mg2+ (0.5-10 mM) and ionic strength (90, 150 mM). In preparations shortened (by 1-3%) to give reduced rigor force, a small transient increase in tension was recorded after ATP release. In comparison to the rates of ATP-induced dissociation of actomyosin in solution, reported in the literature, the rate of relaxation from rigor is slower. This may reflect a slow rigor cross-bridge dissociation or mechanical interactions not associated with cross-bridges in the muscle fibre.(ABSTRACT TRUNCATED AT 250 WORDS) | lld:pubmed |
| pubmed-article:3429640 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3429640 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3429640 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:3429640 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3429640 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:3429640 | pubmed:issn | 0142-4319 | lld:pubmed |
| pubmed-article:3429640 | pubmed:author | pubmed-author:RüeggJ CJC | lld:pubmed |
| pubmed-article:3429640 | pubmed:author | pubmed-author:GoodyR SRS | lld:pubmed |
| pubmed-article:3429640 | pubmed:author | pubmed-author:ArnerAA | lld:pubmed |
| pubmed-article:3429640 | pubmed:author | pubmed-author:RappGG | lld:pubmed |
| pubmed-article:3429640 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3429640 | pubmed:volume | 8 | lld:pubmed |
| pubmed-article:3429640 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3429640 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3429640 | pubmed:pagination | 377-85 | lld:pubmed |
| pubmed-article:3429640 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:3429640 | pubmed:meshHeading | pubmed-meshheading:3429640-... | lld:pubmed |
| pubmed-article:3429640 | pubmed:meshHeading | pubmed-meshheading:3429640-... | lld:pubmed |
| pubmed-article:3429640 | pubmed:meshHeading | pubmed-meshheading:3429640-... | lld:pubmed |
| pubmed-article:3429640 | pubmed:meshHeading | pubmed-meshheading:3429640-... | lld:pubmed |
| pubmed-article:3429640 | pubmed:meshHeading | pubmed-meshheading:3429640-... | lld:pubmed |
| pubmed-article:3429640 | pubmed:meshHeading | pubmed-meshheading:3429640-... | lld:pubmed |
| pubmed-article:3429640 | pubmed:meshHeading | pubmed-meshheading:3429640-... | lld:pubmed |
| pubmed-article:3429640 | pubmed:meshHeading | pubmed-meshheading:3429640-... | lld:pubmed |
| pubmed-article:3429640 | pubmed:meshHeading | pubmed-meshheading:3429640-... | lld:pubmed |
| pubmed-article:3429640 | pubmed:year | 1987 | lld:pubmed |
| pubmed-article:3429640 | pubmed:articleTitle | Relaxation of chemically skinned guinea pig taenia coli smooth muscle from rigor by photolytic release of adenosine-5'-triphosphate. | lld:pubmed |
| pubmed-article:3429640 | pubmed:affiliation | Physiologisches Institut der Universität Heidelberg, F.R.G. | lld:pubmed |
| pubmed-article:3429640 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3429640 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:3429640 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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