Linked Life Data

3428403

Source:http://linkedlifedata.com/resource/pubmed/id/3428403

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1988-3-23
pubmed:abstractText
Several osmotic cataract models as well as human diabetic lenses were tested by nuclear magnetic resonance spectroscopy and imaging. Both longitudinal (T1) and transverse (T2) relaxation times increased with increase in lens hydration. Therefore proton magnetic resonance imaging (MRI) can be used to detect changes of the biophysical environment of water proton in the lens. T2-weighted imaging sequence (spin-echo) can be used to differentiate lenses with hydrational changes since they exhibit higher signal intensity (because of long T2) than normal lenses at the same TE (echo time). A greater contrast can be achieved with the inversion-recovery sequence, which, in addition to contribution from T2, also incorporates T1 and proton density terms. Proton MRI is potentially useful for the detection of pre-cataractous changes.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0014-4835
pubmed:author
pubmed:issnType
Print
pubmed:volume
45
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
875-82
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Proton magnetic resonance imaging of the ocular lens.
pubmed:affiliation
Howe Laboratory of Ophthalmology, Harvard Medical School, Boston, MA 02114.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't