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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3-4
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pubmed:dateCreated |
1988-2-25
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pubmed:abstractText |
27-day-old female rats received 20 IU PMS and 56 hours later, 40 IU hCG and were orally given with 20 or 200 micrograms of Hachimijiogan (TJ-7), Tokishakuyakusan (TJ-23) or Keishibukuryogan (TJ-25) daily for 3 or 5 days before sacrifice. Seven days after hCG treatment, the serum and ovarian tissue were assayed for progestins. 200 micrograms/day of TJ-23 significantly (p less than 0.05) decreased the progesterone and 17 alpha-hydroxyprogesterone levels, whereas it significantly (p less than 0.01) increased 20 alpha-hydroxyprogesterone. TJ-7 and TJ-25 showed a tendency to decrease these progestins. These results suggest that TJ-23 has a luteolytic effect on the corpus luteum in vivo.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Benzoic Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Bridged Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/Chorionic Gonadotropin,
http://linkedlifedata.com/resource/pubmed/chemical/Drugs, Chinese Herbal,
http://linkedlifedata.com/resource/pubmed/chemical/Glucosides,
http://linkedlifedata.com/resource/pubmed/chemical/Glycosides,
http://linkedlifedata.com/resource/pubmed/chemical/Gonadotropins, Equine,
http://linkedlifedata.com/resource/pubmed/chemical/Plant Extracts,
http://linkedlifedata.com/resource/pubmed/chemical/Progesterone,
http://linkedlifedata.com/resource/pubmed/chemical/hachimijiogan,
http://linkedlifedata.com/resource/pubmed/chemical/keishibukuryogan,
http://linkedlifedata.com/resource/pubmed/chemical/peoniflorin
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pubmed:status |
MEDLINE
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pubmed:issn |
0192-415X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
99-108
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3425577-Animals,
pubmed-meshheading:3425577-Benzoic Acids,
pubmed-meshheading:3425577-Bridged Compounds,
pubmed-meshheading:3425577-Chorionic Gonadotropin,
pubmed-meshheading:3425577-Corpus Luteum,
pubmed-meshheading:3425577-Drugs, Chinese Herbal,
pubmed-meshheading:3425577-Female,
pubmed-meshheading:3425577-Glucosides,
pubmed-meshheading:3425577-Glycosides,
pubmed-meshheading:3425577-Gonadotropins, Equine,
pubmed-meshheading:3425577-Organ Size,
pubmed-meshheading:3425577-Organ Specificity,
pubmed-meshheading:3425577-Plant Extracts,
pubmed-meshheading:3425577-Progesterone,
pubmed-meshheading:3425577-Rats,
pubmed-meshheading:3425577-Rats, Inbred Strains
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pubmed:year |
1987
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pubmed:articleTitle |
Effects of hachimijiogan, tokishakuyakusan and keishibukuryogan on the corpus luteum function and weights of various organs in vivo.
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pubmed:affiliation |
Department of Obstetrics and Gynecology, University of Tsukuba, Ibaraki, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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