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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1988-2-10
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pubmed:abstractText |
An enhancer of the human beta-actin gene and a factor that specifically interacts with it were detected. A mobility shift assay showed that the factor bound to the 25-base-pair sequence (between +759 and +783 downstream from the cap site) with high specificity. This finding correlated with those of DNase I protection and exonuclease III digestion assays. This binding region of the beta-actin enhancer contained a hyphenated dyad symmetry and an enhancer core-like sequence. In vitro competition experiments indicated that the factor did not bind to the simian virus 40 enhancer core region.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-212715,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-2942943,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-2982105,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-2992804,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-2993917,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-2994062,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-2996885,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-3006925,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-3027566,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-3031671,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-3034433,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-3079885,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-3095662,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-3462701,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-3463962,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-3524858,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-3529394,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-3561411,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-3785168,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-3837182,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-3917575,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-4705382,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-6187469,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-6246368,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-6269071,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-6275366,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-6290669,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-6292901,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-6297005,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-6300777,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-6324080,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-6933441,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3422098-6960240
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0270-7306
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
267-72
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:3422098-Acetyltransferases,
pubmed-meshheading:3422098-Actins,
pubmed-meshheading:3422098-Binding Sites,
pubmed-meshheading:3422098-Chloramphenicol O-Acetyltransferase,
pubmed-meshheading:3422098-DNA Mutational Analysis,
pubmed-meshheading:3422098-DNA-Binding Proteins,
pubmed-meshheading:3422098-Deoxyribonuclease I,
pubmed-meshheading:3422098-Enhancer Elements, Genetic,
pubmed-meshheading:3422098-Exodeoxyribonucleases,
pubmed-meshheading:3422098-Gene Expression Regulation,
pubmed-meshheading:3422098-Humans,
pubmed-meshheading:3422098-Introns,
pubmed-meshheading:3422098-Regulatory Sequences, Nucleic Acid,
pubmed-meshheading:3422098-Transcription Factors
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pubmed:year |
1988
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pubmed:articleTitle |
Identification of the human beta-actin enhancer and its binding factor.
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pubmed:affiliation |
Department of Oncogene Research, Osaka University, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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