Linked Life Data

3421169

Source:http://linkedlifedata.com/resource/pubmed/id/3421169

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10 Pt 1
pubmed:dateCreated
1988-10-27
pubmed:abstractText
The relation between family history of coronary artery disease (CAD) and coronary risk variables was examined in 1,058 Utah adults. Subjects were divided into 3 family history score groups (low, intermediate and high) and the effects of 60 potential risk variables were assessed using multiple stepwise discriminant analysis. After controlling for age effects, the variables entering the discriminant function equation (p less than 0.01) were cholesterol, years smoking cigarettes, high-density lipoprotein cholesterol and triceps skinfold thickness. Although normal blood pressure variation did not discriminate among family history groups, those with a positive family history of CAD were more likely to develop hypertension than those without a family history (age-adjusted relative risk 1.79, with 95% confidence limits 1.03 and 3.09). In spite of significant differences among family history score groups with regard to risk variables, the discriminant analysis classified only 39% of subjects into the correct group. It was concluded that other unknown risk variables must mediate the effects of family history of CAD. Thus, family history should be considered an independent risk factor for CAD.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0002-9149
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
62
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
708-13
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Relation between family history of coronary artery disease and coronary risk variables.
pubmed:affiliation
Department of Human Genetics, University of Utah School of Medicine, Salt Lake City 84132.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.