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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1988-10-25
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pubmed:abstractText |
Newborn female and male C57BL6 mice were decapitated at birth or at different times during the first 24 h after birth and testosterone was determined by radioimmunoassay in plasma and testes. In newborn females, plasma testosterone is low and does not significantly change over the first 24 h after birth. In contrast, in newborn males, plasma testosterone more than doubles during the first 2 h after birth and then falls rapidly to remain relatively low for the remainder of the 24 h period after birth. The increase in plasma testosterone is of almost certain testicular origin since it follows a decrease in testicular testosterone content. It seems likely that the increase in plasma testosterone in male mice which reaches its peak at 2 h after birth is involved in an essential way in the development of well-documented sex differences in gonadotropin secretion and behavior.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0022-4731
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
283-6
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:3419158-Aging,
pubmed-meshheading:3419158-Androstenedione,
pubmed-meshheading:3419158-Animals,
pubmed-meshheading:3419158-Animals, Newborn,
pubmed-meshheading:3419158-Female,
pubmed-meshheading:3419158-Male,
pubmed-meshheading:3419158-Mice,
pubmed-meshheading:3419158-Mice, Inbred C57BL,
pubmed-meshheading:3419158-Radioimmunoassay,
pubmed-meshheading:3419158-Reference Values,
pubmed-meshheading:3419158-Sex Factors,
pubmed-meshheading:3419158-Testis,
pubmed-meshheading:3419158-Testosterone
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pubmed:year |
1988
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pubmed:articleTitle |
Testosterone levels in plasma and testes of neonatal mice.
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pubmed:affiliation |
Laboratoire d'Endocrinologie, Université Paris XI, Orsay, France.
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pubmed:publicationType |
Journal Article
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