Linked Life Data

3417358

Source:http://linkedlifedata.com/resource/pubmed/id/3417358

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1988-10-24
pubmed:abstractText
The hypothesis that obesity plays a role in the prognosis of breast cancer is examined in this preliminary analysis of a follow-up study of 472 early-stage breast cancer patients. The 75th percentile values of weight (= 73 kg) and body mass index (BMI = 28) in the total patient population were taken as the cut points for estimating overweight or "obesity". Stratified, survival, and logistic regression analyses showed that increased weight or BMI, but not height, were associated with increased risk recurrence. In the logistic regression analysis, after accounting for other risk factors, stage III was a negative prognostic indicator of recurrence (with stage I as the referent group, OR = 3.46, 95% CI: 1.36-8.81). Women whose weights were above the 75th percentile value had a significantly increased risk of recurrence in relation to the other women (OR = 3.55, 95% CI: 1.65-7.65). Results from a model substituting BMI for weight showed a similar significant result. The adequacy of using anthropometric indices as proxies for obesity and various biological mechanisms, which may explain the relationship, are discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0020-7136
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
42
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
315-8
pubmed:dateRevised
2007-7-24
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Weight, height and body mass index in the prognosis of breast cancer: early results of a prospective study.
pubmed:affiliation
American Health Foundation, Division of Epidemiology, New York, NY 10017.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't