Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1988-10-21
pubmed:abstractText
Specific features of 2-ethyl-6-methyl-3-hydroxypyridine (3-OP) action were investigated in white rats. A correlation has been established between pharmacokinetic parameters and basic manifestations of psychotropic 3-OP effect. Correlations have been also observed between the level of manifestation of anxiolytic effect and changes in 3-OP concentrations in the rat brain. Electroencephalographic findings of the nootropic effect in sensorimotor cortex correlate with 3-OP brain concentrations. The authors describe specific drug pharmacokinetics and possible mechanisms of realization of psychotropic effects.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0365-9615
pubmed:author
pubmed:issnType
Print
pubmed:volume
106
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
165-7
pubmed:dateRevised
2008-10-8
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
[Pharmacokinetic, behavioral and neurophysiological aspects of the action of 2-ethyl-6-methyl-3-hydroxypyridine in rats].
pubmed:publicationType
Journal Article, English Abstract