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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1988-10-3
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pubmed:abstractText |
Phenylpropanolamine is widely used and freely available without a doctor's prescription in drug and grocery stores; it is the active ingredient in most diet aids and many cold preparations. Several cases of multiple cerebral hemorrhages associated with transient hypertension have recently been attributed to phenylpropanolamine in dosages equal to or less than that contained in two diet aids (i.e., 150 mg). Some evidence also exists on the additive effects of the co-ingestion of phenylpropanolamine and caffeine. We therefore undertook a study to demonstrate that a significant health risk can be caused by a double dose of a typical over-the-counter (OTC) diet aid (i.e., 150 mg phenylpropanolamine) and also when 75 mg phenylpropanolamine is taken with caffeine.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0002-9343
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
85
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
339-43
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:3414729-Adult,
pubmed-meshheading:3414729-Blood Pressure,
pubmed-meshheading:3414729-Caffeine,
pubmed-meshheading:3414729-Delayed-Action Preparations,
pubmed-meshheading:3414729-Double-Blind Method,
pubmed-meshheading:3414729-Drug Interactions,
pubmed-meshheading:3414729-Female,
pubmed-meshheading:3414729-Humans,
pubmed-meshheading:3414729-Hypertension,
pubmed-meshheading:3414729-Male,
pubmed-meshheading:3414729-Monitoring, Physiologic,
pubmed-meshheading:3414729-Phenylpropanolamine,
pubmed-meshheading:3414729-Random Allocation
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pubmed:year |
1988
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pubmed:articleTitle |
A double dose of phenylpropanolamine causes transient hypertension.
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pubmed:affiliation |
Department of Psychiatry, Uniformed Services University of the Health Sciences, F. Edward Hebert School of Medicine, Bethesda, Maryland 20814-4799.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Randomized Controlled Trial
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