rdf:type |
|
lifeskim:mentions |
umls-concept:C0015811,
umls-concept:C0021102,
umls-concept:C0025914,
umls-concept:C0026809,
umls-concept:C0026845,
umls-concept:C0032160,
umls-concept:C0053932,
umls-concept:C0205199,
umls-concept:C0871261,
umls-concept:C1704229,
umls-concept:C1704632,
umls-concept:C1705604,
umls-concept:C1706817,
umls-concept:C2911692
|
pubmed:issue |
234
|
pubmed:dateCreated |
1988-10-4
|
pubmed:abstractText |
A composite consisting of 1 mg of bone morphogenetic protein (BMP) and 5 mg of plaster of Paris (PLP) was implanted into the mouse femoral muscle. Control PLP without BMP was implanted into the contralateral muscle. The BMP/PLP composite induced cartilage formation within two weeks, trabecular bone within three weeks, and lamellar bone including bone marrow within six weeks. PLP did not disturb BMP-induced bone formation. In addition, the BMP/PLP composite was resorbed early after implantation. These results suggest that PLP composite system is one of the most suitable BMP delivery systems currently available.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0009-921X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
240-9
|
pubmed:dateRevised |
2005-3-3
|
pubmed:meshHeading |
pubmed-meshheading:3409582-Animals,
pubmed-meshheading:3409582-Bone Morphogenetic Proteins,
pubmed-meshheading:3409582-Bone and Bones,
pubmed-meshheading:3409582-Calcium Sulfate,
pubmed-meshheading:3409582-Cartilage,
pubmed-meshheading:3409582-Drug Implants,
pubmed-meshheading:3409582-Growth Substances,
pubmed-meshheading:3409582-Mice,
pubmed-meshheading:3409582-Muscles,
pubmed-meshheading:3409582-Osteogenesis,
pubmed-meshheading:3409582-Proteins
|
pubmed:year |
1988
|
pubmed:articleTitle |
Response of the mouse femoral muscle to an implant of a composite of bone morphogenetic protein and plaster of Paris.
|
pubmed:affiliation |
First Department of Oral Surgery, Faculty of Dentistry, Tokyo Medical and Dental University, Japan.
|
pubmed:publicationType |
Journal Article
|