Linked Life Data

3408441

Source:http://linkedlifedata.com/resource/pubmed/id/3408441

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1988-9-22
pubmed:abstractText
Ten male albino rabbits were implanted with stimulating electrodes in the lateral reticular nucleus (LRN). These rabbits were given paired classical conditioning training of the nictitating membrane response with stimulation of the LRN as the conditioned stimulus (CS) Each rabbit was given daily training sessions until it consistently made conditioned responses (CRs). Each rabbit then received an aspiration lesion of cerebellar cortex; the ipsilateral anso-paramedian lobule (n = 6), the anterior or central vermis (n = 2), the central vermis and ansiform lobule (n = 1), or the central vermis and paramedian lobule (n = 1). After recovery, these rabbits were again given paired classical conditioning training with LRN stimulation as the CS. The rabbits with anso-paramedian lesions did not retain the CR after the lesion, but were able to relearn it. The rabbits with lesions of the vermis, the vermis and ansiform, or the vermis and paramedian retained the CR after the lesion. These results are contrasted with previous results, which show that after aspiration of the anso-paramedian lobule, the conditioned response is not retained or relearned when stimulation of the dorsolateral pontine nucleus (DLPN) is used as a CS. The differences between the mossy fiber outputs of the LRN and DLPN may account for this discrepancy. Different regions of the cerebellum are apparently involved in retention of classically conditioned responses depending on the population of mossy fibers carrying the CS information.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0163-1047
pubmed:author
pubmed:issnType
Print
pubmed:volume
49
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
293-301
pubmed:dateRevised
2006-5-16
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
The effect of lesions of cerebellar cortex on retention of the classically conditioned eyeblink response when stimulation of the lateral reticular nucleus is used as the conditioned stimulus.
pubmed:affiliation
Department of Psychology, University of Southern California, Los Angeles 90089.
pubmed:publicationType
Journal Article