Linked Life Data

3407417

Source:http://linkedlifedata.com/resource/pubmed/id/3407417

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1988-9-21
pubmed:abstractText
We established that Cu(II) and its complexes with aspirin, indomethacin and cimetidine produced lipid peroxidation in phosphatidylcholine suspension. Ionic copper was found to have the most pronounced effect, while the effect of the complexes depends on the ligand. Neither of the ligands exerted a prooxidative effect. NADH sharply increased the effects of Cu(II) and its complexes. In contrast, in the presence of ascorbate the prooxidative effect of Cu(II) and its complexes decreased. Cu(II) and its complexes strongly inhibited ascorbate-induced lipid peroxidation. Using antioxidant substances, enzymes and copper-chelating agents, we attempted to explain the observed effects of Cu(II) and its complexes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0323-9950
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
52-9
pubmed:dateRevised
2000-12-18
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Phosphatidylcholine peroxidation induced by Cu(II) and some Cu(II) complexes.
pubmed:affiliation
Institute of Physiology, Bulgarian Academy of Sciences, Sofia.
pubmed:publicationType
Journal Article