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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1988-9-21
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pubmed:databankReference | |
pubmed:abstractText |
Mycoplasma capricolum uses two tryptophan codons, the "universal" nonsense codon UGA and the universal codon UGG. The bacterium contains two tryptophan tRNAs, one with anticodon UCA, (U: 2'-O-methyl U derivative), and the other with CCA (5'-C: partially 2'-O-methylated). tRNAUCA would translate codons UGA and probably UGG by wobbling. tRNACCA is much less charged by tryptophan in the cells than tRNAUCA, and the intracellular amount of tRNACCA is 5-10 times lower than that of tRNAUCA. The genes for these two tRNAs are separated by a terminator-like structure in a single operon. In vitro transcription experiments suggest that the predominance of tRNAUCA over tRNACCA results from the attenuation of transcription by this terminator-like structure.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0026-8925
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
212
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
364-9
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:3405203-Base Sequence,
pubmed-meshheading:3405203-Biological Evolution,
pubmed-meshheading:3405203-DNA-Directed RNA Polymerases,
pubmed-meshheading:3405203-Gene Expression Regulation,
pubmed-meshheading:3405203-Genes, Bacterial,
pubmed-meshheading:3405203-Molecular Sequence Data,
pubmed-meshheading:3405203-Mycoplasma,
pubmed-meshheading:3405203-Nucleic Acid Conformation,
pubmed-meshheading:3405203-Plasmids,
pubmed-meshheading:3405203-RNA, Transfer, Amino Acid-Specific,
pubmed-meshheading:3405203-RNA, Transfer, Trp,
pubmed-meshheading:3405203-Transcription, Genetic
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pubmed:year |
1988
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pubmed:articleTitle |
Evolutionary dynamics of tryptophan tRNAs in Mycoplasma capricolum.
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pubmed:affiliation |
Department of Biology, Faculty of Science, Nagoya University, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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