Linked Life Data

3401802

Source:http://linkedlifedata.com/resource/pubmed/id/3401802

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1988-9-15
pubmed:abstractText
The survival and organization of embryonic and postnatal cerebellum transplanted into intracephalic cavities in adult rat hosts was studied before and after growth as explants in tissue culture. It is well known that embryonic cerebellum survives transplantation and develops a typical cerebellar cytoarchitecture. This study demonstrates that early postnatal cerebellum survives transplantation poorly if at all using the intracephalic transplant paradigm. Postnatal cerebellum is capable of extensive growth and organization in explant culture; however, prior growth in explant culture did not enhance survival in the transplant situation. On the other hand, embryonic cerebellum grown in explant culture for as long as two weeks, to an age comparable to the postnatal cerebellar transplants, survives transplantation and develops similar cytoarchitectural features to directly transplanted embryonic cerebellum.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
469
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
253-61
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Survival and development of embryonic and postnatal cerebellum transplanted into adult rat hosts: effect of growth as explants in culture prior to transplantation.
pubmed:affiliation
Department of Anatomy and Neurobiology, University of Vermont, College of Medicine, Burlington 05405.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.