Linked Life Data

3401716

Source:http://linkedlifedata.com/resource/pubmed/id/3401716

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1988-9-15
pubmed:abstractText
The influence of prolactin (Prl) and bromocriptine on the specific activities of neural and glial cellular enzymes involved in carbohydrate metabolism in cerebral cortex, hypothalamus, cerebellum and pons-medulla was studied. Both Prl and bromocriptine stimulated the activity of hexokinase (HK) in the neural as well as in the glial cells. While Prl increased the activity of phosphofructokinase (PFK), glyceraldehyde-3-phosphate dehydrogenase (G-3-PDH) and pyruvate kinase (PK) in the neural cells, it decreased the same in the glial cells. On the other hand, bromocriptine elevated the activity of all these enzymes in the neural cells without any effect on the glial cells. The activities of neural cellular glucose-6-phosphate dehydrogenase (G-6-PDH) and 6-phosphogluconate dehydrogenase (6-PGDH) were inhibited by Prl, whereas bromocriptine increased the same. The activities of these enzymes in the glial cells were enhanced by both Prl and bromocriptine. Thus, the present study suggests that Prl has a differential effect on the activities of enzymes involved in Embden-Meyerhoff pathway (EMP) and hexosemonophosphate shunt (HMP) in the neural and glial cells of immature male bonnet monkeys.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
31
pubmed:volume
450
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
325-33
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Role of prolactin on neural and glial cellular enzymes involved in carbohydrate metabolism. I. Studies on immature male bonnet monkeys.
pubmed:affiliation
Department of Endocrinology, University of Madras, Taramani, India.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't