Linked Life Data

3401135

Source:http://linkedlifedata.com/resource/pubmed/id/3401135

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1988-9-1
pubmed:abstractText
Elderly patients with drusen and good visual acuity have a decrease in dark-adapted retinal sensitivity in the central retina. We used the fundus camera stimulator to determine whether this sensitivity loss is caused directly by the presence of drusen. We measured retinal sensitivity over drusen and in drusen-free areas in eight patients with drusen and age-related macular degeneration (AMD). There was no significant difference in sensitivity between drusen and nondrusen areas in each patient. The sensitivity loss seen in patients with drusen thus seems to reflect a more diffuse disease of the retina and retinal pigment epithelium and is not a direct effect of drusen. More marked sensitivity losses are found in even small areas of more advanced AMD changes, suggesting that a large focal loss in retinal sensitivity may be an indicator of developing AMD changes.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0003-9950
pubmed:author
pubmed:issnType
Print
pubmed:volume
106
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1081-4
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Retinal sensitivity over drusen and nondrusen areas. A study using fundus perimetry.
pubmed:affiliation
Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.