Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1988-9-7
pubmed:abstractText
Six children with membranoproliferative glomerulonephritis Type II (MPGN II-dense deposit disease), who were followed an average of 14 years (3.5 to 22 years) and treated continuously with an alternate-day prednisone regimen, have been studied by successive renal biopsies over intervals of 2 to 14 years of disease. All have shown significant reduction in mesangial proliferation and improvement of capillary lumen patency. A change in position of the deposits, from the lamina densa to the lamina rara interna, was demonstrated ultrastructurally in four of the patients, accompanied by reduction in prevalence of deposit in three. This loss of dense deposits, characterized as a process of "dropping off," was complete in the free capillary walls of two of the patients.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0272-6386
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
138-46
pubmed:dateRevised
2005-11-17
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Regression of membranoproliferative glomerulonephritis type II (dense deposit disease): observations in six children.
pubmed:affiliation
Division of Pediatric Nephrology, Children's Hospital Medical Center, Cincinnati, OH 45229.
pubmed:publicationType
Journal Article