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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1988-8-30
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pubmed:abstractText |
The erythrocyte 2,3-diphosphoglycerate concentration (2,3-DPG) and the activity of red cell hexokinase, pyruvate kinase, glucose-6 phosphate dehydrogenase and glutathione reductase were studied in 27 normal volunteers before and after 2 and 4 months of physical endurance training. The 4 months of training increased maximal oxygen uptake and physical working capacity (PWC130) by 16% (p less than 0.001) and 29% (p less than 0.001) respectively. Resting heart rate was decreased (p less than 0.001) by 11 beats.min-1. With 2 months of training the erythrocyte 2,3-DPG concentration increased by 9% (p less than 0.001); with 4 months training the increase was only 4% (p less than 0.05). The training-induced increase in red cell 2,3-DPG was not accompanied by enhanced activity of erythrocyte hexokinase, pyruvate kinase, glucose-6 phosphate dehydrogenase or glutathione reductase. It is concluded that the rise in red cell 2,3-DPG induced by physical endurance training is not due to activation of red cell glycolytic enzymes or the enzymes involved in the pentose-phosphate cycle.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0301-5548
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
57
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
456-61
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3396560-2,3-Diphosphoglycerate,
pubmed-meshheading:3396560-Adult,
pubmed-meshheading:3396560-Diphosphoglyceric Acids,
pubmed-meshheading:3396560-Erythrocytes,
pubmed-meshheading:3396560-Humans,
pubmed-meshheading:3396560-Male,
pubmed-meshheading:3396560-Middle Aged,
pubmed-meshheading:3396560-Physical Education and Training,
pubmed-meshheading:3396560-Physical Endurance,
pubmed-meshheading:3396560-Reference Values
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pubmed:year |
1988
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pubmed:articleTitle |
Effects of training on erythrocyte 2,3-diphosphoglycerate in normal men.
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pubmed:affiliation |
Department of Pathophysiology, University of Leuven (K. U.-Leuven), Belgium.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|