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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1988-9-1
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pubmed:abstractText |
A 74-year-old Japanese male with a 4-year history of refractory anemia with excess of blasts is reported here. Chromosome study revealed the bone marrow cells of this patient to contain a t(3;4)(q26;q21). Ultrastructural analysis of platelet peroxidase and immunocytochemical study using monoclonal antibody for platelet antigen revealed a large number of blasts in the bone marrow to be megakaryoblasts. Thus, this case was thought to be one of a myelodysplastic syndrome with excess of blasts including megakaryoblastic proliferation showing chromosome changes at 3q26 and 4q21. The relationship of the anomaly on the long arm of a chromosome #3, especially at band 3q26, to abnormal megakaryoblastic proliferation is discussed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0165-4608
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
5-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3395994-Aged,
pubmed-meshheading:3395994-Blood Platelets,
pubmed-meshheading:3395994-Bone Marrow,
pubmed-meshheading:3395994-Cell Division,
pubmed-meshheading:3395994-Chromosome Banding,
pubmed-meshheading:3395994-Chromosomes, Human, Pair 3,
pubmed-meshheading:3395994-Chromosomes, Human, Pair 4,
pubmed-meshheading:3395994-Humans,
pubmed-meshheading:3395994-Karyotyping,
pubmed-meshheading:3395994-Male,
pubmed-meshheading:3395994-Megakaryocytes,
pubmed-meshheading:3395994-Myelodysplastic Syndromes,
pubmed-meshheading:3395994-Peroxidases,
pubmed-meshheading:3395994-Translocation, Genetic
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pubmed:year |
1988
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pubmed:articleTitle |
Translocation t(3;4)(q26;q21) in myelodysplastic syndrome with megakaryoblastic proliferation.
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pubmed:affiliation |
Department of Internal Medicine, Tokyo Medical College, Japan.
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
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