Linked Life Data

3395467

Source:http://linkedlifedata.com/resource/pubmed/id/3395467

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1988-8-29
pubmed:abstractText
Adult male Sprague-Dawley rats were maintained on an ad lib diet containing 100 ppm cadmium (Group Cadmium-Diet) or a control diet with no added cadmium. On Day 61, all animals (N = 10/group) were challenged with a single hypnotic dose of ethanol (3.5 g/kg IP), prepared from a 20% v/v solution of tap water and a stock solution of 95% ethanol. The latency from the time of the injection until the loss of the righting reflex was recorded, as well as the latency for recovery of the reflex. The results showed a nonsignificant trend for animals exposed to cadmium to lose the righting reflex less rapidly than controls, and Cadmium-Diet animals regained the righting reflex significantly more rapidly than controls. These findings suggest that the pharmacologic effectiveness of ethanol is altered by chronic exposure to dietary cadmium. The implications of these data for other studies of cadmium/ethanol interactions are discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0741-8329
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
99-102
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:articleTitle
Cadmium exposure results in decreased responsiveness to ethanol.
pubmed:affiliation
Department of Psychology, Texas A&M University, College Station 77843.
pubmed:publicationType
Journal Article