Linked Life Data

339166

Source:http://linkedlifedata.com/resource/pubmed/id/339166

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1978-2-23
pubmed:abstractText
The effect of metals and drugs on the activity of human erythrocyte ALA dehydratase has been studied in vitro. The most inhibitory metals are with decreasing effect silver, copper, gold and selenium. Zinc, cadmium, mercury are inhibitory at high concentrations and activator at low concentrations. Arsenic, calcium, magnesium, manganese, potassium, cobalt have no effect. Within the drugs studied the non steroidal anti-inflammatory drugs (aspirin, keptoprofen, indometacin, phenylbutazone, sodium salicylate and niflumic acid) are the only group which inhibits the enzyme ALA dehydratase. This inhibition is suppressed by zinc. The non steroidal anti-inflammatory drugs can inhibit the activity of enzymes which need zinc for optimal activity.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0369-8114
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
535-40
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
[Influence of metals and non-steroid anti-inflammatory drugs on the activity of human red cell ALA dehydratase "in vitro" (author's transl)].
pubmed:publicationType
Journal Article, In Vitro, English Abstract