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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
1988-8-4
|
| pubmed:abstractText |
Three propellant chlorofluorocarbons, namely trichlorofluoromethane (FC11), dichlorodifluoromethane (FC12), and chlorodifluoromethane (FC22) were administered by inhalation at a concentration of 5000, 1000 and 0 ppm, 4 hours daily, 5 days weekly, for 104 and 78 weeks, to rats and mice, respectively. The animals were kept under observation until spontaneous death. Under the experimental conditions, all three compounds failed to show any carcinogenic effects.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0077-8923
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
534
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
261-82
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:3389660-Administration, Inhalation,
pubmed-meshheading:3389660-Adrenal Gland Neoplasms,
pubmed-meshheading:3389660-Animals,
pubmed-meshheading:3389660-Biological Assay,
pubmed-meshheading:3389660-Chlorofluorocarbons, Methane,
pubmed-meshheading:3389660-Hemangiosarcoma,
pubmed-meshheading:3389660-Liver Neoplasms,
pubmed-meshheading:3389660-Mammary Neoplasms, Experimental,
pubmed-meshheading:3389660-Mice,
pubmed-meshheading:3389660-Pheochromocytoma,
pubmed-meshheading:3389660-Rats,
pubmed-meshheading:3389660-Rats, Inbred Strains
|
| pubmed:year |
1988
|
| pubmed:articleTitle |
Long-term carcinogenicity bioassays on three chlorofluorocarbons (trichlorofluoromethane, FC11; dichlorodifluoromethane, FC12; chlorodifluoromethane, FC22) administered by inhalation to Sprague-Dawley rats and Swiss mice.
|
| pubmed:affiliation |
Institute of Oncology F. Addarii, Bologna, Italy.
|
| pubmed:publicationType |
Journal Article
|