Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1978-2-18
pubmed:abstractText
Following the demonstration by Chambers (1977a,b and c) that simultaneous attachment of macrophages to endocytogenic material in vitro leads to fusion, as analysis of the phagocytic potential of giant cells has provided evidence that the same mechanism is operating in macrophage polykaryon formation in vovo. Unlike previously proposed models for macrophage fusion, fusion by simultaneous attempted endocytosis is associated with the interiorisation of surface membrane during fusion. This has been shown to have occurred during glass coverslip-induced fusion in vivo. Evidence has also been presented that it is the endocytogenic material produced in the granulomatous environment which leads to fusion, not necessarily the simulaneous attempted endocytosis of the implanted foreign material.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0022-3417
pubmed:author
pubmed:issnType
Print
pubmed:volume
123
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
65-77
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Studies on the phagocytic capacity of macrophage polykaryons.
pubmed:publicationType
Journal Article, In Vitro