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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1988-8-1
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pubmed:abstractText |
An attempt to reduce a radiation-induced conditioned taste aversion (CTA) was undertaken by rendering animals tolerant to ethanol. Ethanol tolerance, developed over 5 days, was sufficient to block a radiation-induced taste aversion, as well as an ethanol-induced CTA. Several intermittent doses of ethanol, which did not induce tolerance but removed the novelty of the conditioning stimulus, blocked an ethanol-induced CTA but not the radiation-induced CTA. A CTA induced by doses of radiation up to 500 rads was attenuated. These data suggest that radioprotection developing in association with ethanol tolerance is a result of a physiological response to the chronic presence of ethanol not to the ethanol itself.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0024-3205
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
59-66
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3386415-Animals,
pubmed-meshheading:3386415-Conditioning, Classical,
pubmed-meshheading:3386415-Drug Tolerance,
pubmed-meshheading:3386415-Ethanol,
pubmed-meshheading:3386415-Gamma Rays,
pubmed-meshheading:3386415-Male,
pubmed-meshheading:3386415-Rats,
pubmed-meshheading:3386415-Rats, Inbred Strains,
pubmed-meshheading:3386415-Sleep,
pubmed-meshheading:3386415-Taste
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pubmed:year |
1988
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pubmed:articleTitle |
Attenuation of a radiation-induced conditioned taste aversion after the development of ethanol tolerance.
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pubmed:affiliation |
Behavioral Sciences Department Armed Forces Radiobiology Research Institute Bethesda, MD 20814-5145.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
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