Linked Life Data

338407

Source:http://linkedlifedata.com/resource/pubmed/id/338407

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1978-2-18
pubmed:abstractText
Ninhydrin, a compound which shares chemical properties strikingly similar to alloxan was found to mimic basically the inhibitory effect of alloxan on glucose-induced insulin release. Exposure of pancreatic islets for five minutes to 85 mumol/l ninhydrin produced approximately ninety percent inhibition of subsequent glucose-induced insulin release without altering basal secretion. Both D-glucose and D-mannose provided substantial protection against the inhibitory effect of ninhydrin, and the alpha anomer of D-glucose was more effective than the beta anomer in preventing ninhydrin inhibition of insulin release. Evidence for a common site of inhibition by ninhydrin and alloxan in the insulin release process is discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0012-186X
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
603-6
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Ninhydrin inhibition of glucose-induced insulin release.
pubmed:publicationType
Journal Article, In Vitro, Research Support, U.S. Gov't, P.H.S.