Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1988-7-22
pubmed:abstractText
We tested for the presence of arginine vasopressin (AVP) receptors in pig cerebral microvessels, cerebral cortex and hippocampus by specific binding methods with [3H]AVP as the ligand. The specific binding of [3H]AVP to all preparations was saturable and Scatchard analysis indicated a single class of high affinity binding sites (dissociation constant of 1-2 nM). Maximal binding capacity in cerebral microvessels was about 60% that of the cerebral cortex; and there were no apparent differences in the maximal binding capacity between cerebral cortex and hippocampus. These findings suggest the existence of AVP receptor sites in cerebral microvessels and support the hypothesis that AVP has a role in the control of the brain microcirculation.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
22
pubmed:volume
87
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
121-6
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Arginine vasopressin receptors in pig cerebral microvessels, cerebral cortex and hippocampus.
pubmed:affiliation
Department of Biochemistry, Medical College of Ohio, Toledo 43699.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't