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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1988-7-15
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pubmed:abstractText |
We examined the effect of increasing work rate, without a corresponding increase in the pressure-time product, on energy cost and inspiratory muscle endurance (Tlim) in five normal subjects during inspiratory resistive breathing. Tidal volume, mean inspiratory mouth pressure, duty cycle, and hence the pressure-time product were kept constant, whereas work rate was varied by changing the frequency of breathing. There was a linear decrease in Tlim of -2.1 +/- 0.5 s.J-1.min-1 (r = 0.87 +/- 0.06) with increasing work rate. The data satisfied a model of energy balance during fatiguing runs (Monod and Scherrer. Ergonomics 8: 329-337, 1965) and were consistent with the hypothesis that the rate of energy supply, or respiratory muscle blood flow, is fixed when the pressure-time product is constant. Our results indicate that during inspiratory resistive breathing against fatiguing loads, work rate determines endurance independently of the pressure-time product. On the basis of the model, our results lead to estimates of respiratory muscle blood flow and available energy stores under the conditions of our experiment.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
8750-7587
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1397-404
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3378975-Adult,
pubmed-meshheading:3378975-Energy Metabolism,
pubmed-meshheading:3378975-Fatigue,
pubmed-meshheading:3378975-Female,
pubmed-meshheading:3378975-Humans,
pubmed-meshheading:3378975-Male,
pubmed-meshheading:3378975-Mathematics,
pubmed-meshheading:3378975-Models, Biological,
pubmed-meshheading:3378975-Pressure,
pubmed-meshheading:3378975-Respiration,
pubmed-meshheading:3378975-Respiratory Muscles,
pubmed-meshheading:3378975-Time Factors
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pubmed:year |
1988
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pubmed:articleTitle |
Pressure-time product, work rate, and endurance during resistive breathing in humans.
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pubmed:affiliation |
Thoracic Medicine Unit, Westmead Hospital, New South Wales, Australia.
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pubmed:publicationType |
Journal Article
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