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pubmed-article:3376501pubmed:abstractTextFat emulsions for parenteral nutrition contain phospholipids of different quantity and quality. They are substrates of lecithin-cholesterol-acyltransferase (LCAT). Two fat emulsions commonly used in parenteral nutrition with different emulsifiers (Intralipid 10%, emulsified with egg phospholipid, and Lipofundin S 10%, emulsified with soya phospholipid) were infused into six healthy volunteers. The products of the LCAT reaction were determined in serum lipoprotein fraction d greater than 1.063. Lecithin (16%) as well as lysolecithin (30%) increased by the same amount during a 4-h infusion of each fat emulsion. The concentrations of lecithin and lysolecithin were still within normal ranges after infusion. The percentage of linoleic acid in cholesterol esters in d greater than 1.063 fraction remained unchanged during infusion of soya phospholipids and decreased 5% during infusion of egg phospholipids. The results indicate an equal LCAT activation by both fat emulsions in man.lld:pubmed
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pubmed-article:3376501pubmed:authorpubmed-author:WolframGGlld:pubmed
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pubmed-article:3376501pubmed:volume27lld:pubmed
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pubmed-article:3376501pubmed:pagination23-9lld:pubmed
pubmed-article:3376501pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:3376501pubmed:year1988lld:pubmed
pubmed-article:3376501pubmed:articleTitle[Phospholipids as emulsifiers in fat emulsions--effect on phospholipids in the serum lipoprotein fraction d greater than 1.063].lld:pubmed
pubmed-article:3376501pubmed:affiliationInstitut für Ernährungswissenschaft, Technischen Universität, München, Freising-Weihenstephan.lld:pubmed
pubmed-article:3376501pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:3376501pubmed:publicationTypeComparative Studylld:pubmed
pubmed-article:3376501pubmed:publicationTypeEnglish Abstractlld:pubmed