Linked Life Data

3370951

Source:http://linkedlifedata.com/resource/pubmed/id/3370951

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1988-7-11
pubmed:abstractText
Different sized polyethylene glycols (PEGs) have been used as probe molecules in studies of size-dependent permeation through the intestinal wall and the glomerular membranes. We have curve-fitted a three-compartment model to the urinary recovery data following intravenous injection of different sized PEG molecules in the pig. The rate constants to and from the extravascular space demonstrate a strong size-dependent selectivity for PEG molecules less than 502 Da, but the rate constants to the urine are almost the same for all PEG molecules. This is discussed in relation to the selectivity in the glomerular filtration, distribution volume, and the use of PEG molecules as tracers in the permeability studies.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0010-4809
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
110-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Characterization of size-dependent exchange of PEG molecules between the blood and extravascular space in the pig.
pubmed:affiliation
Department of Medical Microbiology, University of Linköping, Sweden.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't