Linked Life Data

3370246

Source:http://linkedlifedata.com/resource/pubmed/id/3370246

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1988-7-12
pubmed:abstractText
The rates of distribution of the radioactive precursor label de novo and of the reutilization pathways of inosine monophosphate biosynthesis between adenine and guanine nucleotides in the acid-soluble fraction and RNA from chicken liver were determined. The activity of enzymes involved in inosine monophosphate conversion into adenine or guanine nucleotides or in uric acid biosynthesis was determined. It was shown that in chicken liver the activity of IMP-dehydrogenase and the rate constant for the label ([14C]glycine) incorporation into the guanine nucleotide pool is 3.5 times as high as that of adenyl succinate synthetase and the rate constant for the label liberation into the adenine nucleotide pool. The rate of xanthine synthesis is by one order of magnitude more than that of hypoxanthine and uric acid. The rate of IMP synthesis from [14C]hypoxanthine via the guanine nucleotide pathway is also higher in this case. Hence, in chicken liver IMP oxidation to XMP seems to proceed with a high efficiency and can thus be used, in addition to dephosphorylation, for ammonia extrusion.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0320-9725
pubmed:author
pubmed:issnType
Print
pubmed:volume
53
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
182-7
pubmed:dateRevised
2007-7-23
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
[Pathways of inosine monophosphate transformation in the chicken liver].
pubmed:publicationType
Journal Article, English Abstract