Linked Life Data

3369291

Source:http://linkedlifedata.com/resource/pubmed/id/3369291

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1988-6-20
pubmed:abstractText
From 1977 to 1980, seventy-two children were found to have intrinsic (non-IgE-mediated) asthma. Except for five patients, 4 boys and one girl, who apparently grew out of their asthma, the remaining 67 patients were followed for six years. During the study period, 12 patients, 10 boys and 2 girls, developed extrinsic (IgE-mediated) asthma. Nine of them (75%) had a positive family history of atopic disease, which was only the case in 12 (22%) of the patients who did not develop extrinsic disease. Hence, a change from intrinsic into extrinsic asthma is apparently common in boys, but seems to be rare in girls. In addition, in girls with intrinsic asthma, fixed or declining lung function tests followed by signs of pulmonary hyperinflation and lung fibrosis is common. Further, in the present series of children with intrinsic asthma, 5 patients, 4 girls and 1 boy, developed severe bronchiectasis. The majority of patients, who on repeated chest X-rays showed persistent hyperinflation of the lungs associated with fixed FEV1/FVC levels and a marked increase of serum IgG-concentrations were those at risk to develop severe lung disease.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0001-656X
pubmed:author
pubmed:issnType
Print
pubmed:volume
77
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
112-7
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
A prospective study on non-IgE-mediated asthma in children.
pubmed:affiliation
Department of Paediatrics, Aalborg Hospital North, Denmark.
pubmed:publicationType
Journal Article, Comparative Study