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rdf:type |
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lifeskim:mentions |
umls-concept:C0002131,
umls-concept:C0007582,
umls-concept:C0013018,
umls-concept:C0044222,
umls-concept:C0205147,
umls-concept:C0205171,
umls-concept:C0443288,
umls-concept:C0871261,
umls-concept:C1280500,
umls-concept:C1515655,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2587213,
umls-concept:C2911692
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pubmed:issue |
5
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pubmed:dateCreated |
1978-1-27
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pubmed:abstractText |
Genes in the H-2 complex regulate the relative immunogenicity of the H-7.1 histocompatibility alloantigen, as measured by survival times of H-7.1-incompatible skin grafts in vivo. The gene controlling relative rejectability of H-7.1-incompatible grafts has been mapped to the H-2D region. H-7.1-incompatible skin grafts donated by H-2Db donors were rejected significantly more rapidly by H-2a/H-2b heterozygous recipients than similar H-7.1-incompatible grafts donated by H-2Dd donors. Further, there was absolutely no evidence of H-2 restriction in cytotoxic effector activity. In vivo cross-priming, as indicated by accelerated secondary graft rejection, was extensive. The efficiency of cross-priming was dependent upon the primary and secondary graft donor H-2 haplotypes.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/336833-1079848,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336833-1079924,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336833-1081575,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336833-1083422,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336833-1086219,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336833-123002,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336833-1254962,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336833-13795836,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336833-14057864,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336833-14265497,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336833-233906,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336833-4130130,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336833-4572095,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336833-4579483,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336833-4727915,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336833-4890906,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336833-4926269,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336833-4934351,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336833-53263
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0022-1007
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
146
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1346-55
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:336833-Animals,
pubmed-meshheading:336833-Cell Communication,
pubmed-meshheading:336833-Chromosome Mapping,
pubmed-meshheading:336833-Genes,
pubmed-meshheading:336833-Genetic Linkage,
pubmed-meshheading:336833-Graft Rejection,
pubmed-meshheading:336833-Histocompatibility,
pubmed-meshheading:336833-Histocompatibility Antigens,
pubmed-meshheading:336833-Immunity,
pubmed-meshheading:336833-Mice,
pubmed-meshheading:336833-Mice, Inbred Strains,
pubmed-meshheading:336833-Skin Transplantation,
pubmed-meshheading:336833-Transplantation, Homologous
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pubmed:year |
1977
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pubmed:articleTitle |
H-2 effects on cell-cell interactions in the response to single non-H-2 alloantigens. I. Donor H-2D region control of H-7.1-immunogenicity and lack of restriction in vivo.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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