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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1978-1-27
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pubmed:abstractText |
The inhibitory action of decanoic acid on both Escherichia coli K-12/154 (normal lipopolysaccharide) and E. coli RC59 (defective lipopolysaccharide) was studied. A correlation was found between the doubling time of E. coli 154 growing in different media and the lethal effect of 0.4% decanoic acid on this bacterium. Decanoic acid (0.4%) exerted a lytic action on glucose-starved and NaN3-inhibited cells of E. coli 154 and RC59. Exponentially growing cultures of both strains were not affected by the addition of 0.4% methyldecanoate, but cells of E. coli RC59 reaching the stationary phase were attacked by that compound. A bactericidal action of 0.4% methyldecanoate on exponential E. coli 154 and RC59 was observed when sodium azide was also present in the media. Concentrations lower than 0.01% methyldecanoate had a lytic effect on spheroplasts from E. coli 154 and RC59. These results indicate that the inhibitory action of a non-metabolizable fatty acid on E. coli depends on the cellular metabolic activity and the outer membrane integrity.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/336606-1107472,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336606-13602745,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336606-238956,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336606-4100836,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336606-4129205,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336606-4144517,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336606-4199515,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336606-4242923,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336606-4545009,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336606-4559830,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336606-4590466,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336606-4590475,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336606-4590476,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336606-4597444,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336606-4601163,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336606-4877876,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336606-4901367,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336606-5070086,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336606-776938,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336606-783144,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336606-785063,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336606-793518,
http://linkedlifedata.com/resource/pubmed/commentcorrection/336606-931951
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0021-9193
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
132
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
790-5
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
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pubmed:year |
1977
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pubmed:articleTitle |
Inhibitory action of a non-metabolizable fatty acid on the growth of Escherichia coli: role of metabolism and outer membrane integrity.
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pubmed:publicationType |
Journal Article
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