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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
1988-6-9
|
| pubmed:abstractText |
Human peripheral blood mononuclear cells when cultured for the short term (11 days) produce an optimal IgM plaque-forming cell (PFC) response to sheep erythrocytes, which is dependent on macrophages and T suppressor and helper lymphocytes. With this system we have investigated the PFC response of individuals with rheumatoid arthritis and compared this to the response of normal sex- and age-matched controls and of patients with osteoarthritis. The response of rheumatoid arthritis patients was significantly lower than that of subjects in the other two categories.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0895-0458
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
5
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
266-8
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:3359569-Animals,
pubmed-meshheading:3359569-Arthritis, Rheumatoid,
pubmed-meshheading:3359569-Erythrocytes,
pubmed-meshheading:3359569-Female,
pubmed-meshheading:3359569-Humans,
pubmed-meshheading:3359569-Immunoglobulin M,
pubmed-meshheading:3359569-Leukocytes, Mononuclear,
pubmed-meshheading:3359569-Male,
pubmed-meshheading:3359569-Sheep
|
| pubmed:year |
1988
|
| pubmed:articleTitle |
Mononuclear cells from rheumatoid arthritis patients exhibit a depressed IgM response to sheep erythrocyte stimulation in vitro.
|
| pubmed:affiliation |
Department of Pathology, Medical University of South Carolina, Charleston 29425.
|
| pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
|