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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1988-5-23
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pubmed:abstractText |
Three of five family members experienced symptoms and biochemical evidence of hepatitis that could not be explained on the basis of infectious, metabolic or immunologic disorders of the liver. A history of prolonged ingestion of moderate amounts of vitamin A (20,000 to 45,000 IU per day for 7 to 10 years) was obtained in each of the three family members and was absent in the remaining two unaffected individuals. A liver biopsy performed in one family member confirmed the diagnosis of vitamin A toxicity. This report emphasizes the finding that even moderate amounts of vitamin A, when ingested over a prolonged period of time, can cause significant hepatocellular injury.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0270-9139
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
272-5
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3356407-Adult,
pubmed-meshheading:3356407-Arthritis,
pubmed-meshheading:3356407-Female,
pubmed-meshheading:3356407-Humans,
pubmed-meshheading:3356407-Hypervitaminosis A,
pubmed-meshheading:3356407-Liver,
pubmed-meshheading:3356407-Liver Diseases,
pubmed-meshheading:3356407-Male,
pubmed-meshheading:3356407-Middle Aged,
pubmed-meshheading:3356407-Vitamin A
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pubmed:articleTitle |
Vitamin A hepatotoxicity in multiple family members.
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pubmed:affiliation |
Department of Medicine, University of Calgary, Alberta, Canada.
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pubmed:publicationType |
Journal Article,
Case Reports
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