Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1988-5-17
|
pubmed:abstractText |
We have cytogenetically investigated short-term cultures initiated from 34 uterine leiomyomas, all of which were histologically completely benign. Clonal chromosome abnormalities were detected in five cases, a normal female complement in 22, whereas, in the remaining seven tumors no karyotype could be established. Apparently identical reciprocal translocations, t(12;14)(q14-15;q23-24), were found as the sole abnormality in four tumors. The fifth abnormal case contained a t(2;14)(p11;p11). We conclude that chromosome aberrations may be found in myomas of the uterus, and that t(12;14)(q14-15;q23-24) characterizes a subset of these tumors.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0165-4608
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
32
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
13-7
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:3355995-Chromosome Banding,
pubmed-meshheading:3355995-Chromosomes, Human, Pair 12,
pubmed-meshheading:3355995-Chromosomes, Human, Pair 14,
pubmed-meshheading:3355995-Female,
pubmed-meshheading:3355995-Humans,
pubmed-meshheading:3355995-Karyotyping,
pubmed-meshheading:3355995-Leiomyoma,
pubmed-meshheading:3355995-Translocation, Genetic,
pubmed-meshheading:3355995-Uterine Neoplasms
|
pubmed:year |
1988
|
pubmed:articleTitle |
A specific translocation, t(12;14)(q14-15;q23-24), characterizes a subgroup of uterine leiomyomas.
|
pubmed:affiliation |
Department of Clinical Genetics, University Hospital, Lund, Sweden.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|